554 lines
8.7 KiB
JSON
554 lines
8.7 KiB
JSON
{
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"summary": [
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{
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"claim": "AA = INF axis",
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"rows": [
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{
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"design": "Bulk disease (GSE68801, n=122)",
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{
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},
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{
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"design": "Drug-perturbation (GSE167360, 5 JAK-i)",
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"metric": "INF signature \u2193",
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},
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{
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"design": "Single-cell (GSE212450+GSE316832)",
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"metric": "non-replicating (capture bias)",
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"p": null,
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"strong": false
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}
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]
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},
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{
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"claim": "AGA = DP Wnt suppression",
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"rows": [
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{
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"design": "Single-cell DP (GSE295410)",
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"p": 4e-79,
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{
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{
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"claim": "Treatment timing",
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{
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"design": "CT.gov trajectories (THRIVE-AA SALT)",
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{
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"claim": "Causal direction",
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{
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"design": "340 perturbation\u2192outcome (199 papers)",
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"t": "AA disease infl\u2191",
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{
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"t": "AA disease hair\u2193",
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{
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"t": "AA treat infl\u2193",
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{
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"t": "AA treat hair\u2191",
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{
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"t": "AA JAK-i INF\u2193",
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"p": 0.0196
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{
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"t": "AGA hair\u2193",
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"dz": "AGA",
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"p": 0.0041
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},
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{
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"t": "AGA DHT\u2192DKK1\u2191",
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"dz": "AGA",
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"p": 0.0011
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},
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{
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"t": "AGA DP Lef1\u2193(sc)",
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"p": 4e-79
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2.6
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1.0,
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0.9,
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7.0,
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1.6,
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0.4,
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4.3
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2.9,
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2.2,
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6.1,
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2.2,
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6.2,
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2.1,
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0.0,
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4.1,
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0.3
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}
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{
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3,
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4,
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"labels": [
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